Magnetic Fields in Stellar Jets

Although several lines of evidence suggest that jets from young stars are driven magnetically from accretion disks, existing observations of field strengths in the bow shocks of these flows imply that magnetic fields play only a minor role in the dynamics at these locations. To investigate this apparent discrepancy we performed numerical simulations of expanding magnetized jets with stochastically variable input velocities with the AstroBEAR MHD code. Because the magnetic field B is proportional to the density n within compression and rarefaction regions, the magnetic signal speed drops in rarefactions and increases in the compressed areas of velocity-variable flows. In contrast, B ~ n^0.5 for a steady-state conical flow with a toroidal field, so the Alfven speed in that case is constant along the entire jet. The simulations show that the combined effects of shocks, rarefactions, and divergent flow cause magnetic fields to scale with density as an intermediate power 1 > p > 0.5. Because p > 0.5, the Alfven speed in rarefactions decreases on average as the jet propagates away from the star. This behavior is extremely important to the flow dynamics because it means that a typical Alfven velocity in the jet close to the star is significantly larger than it is in the rarefactions ahead of bow shocks at larger distances, the one place where the field is a measurable quantity. We find that the observed values of weak fields at large distances are consistent with strong fields required to drive the observed mass loss close to the star. For a typical stellar jet the crossover point inside which velocity perturbations of 30 - 40 km/s no longer produce shocks is ~ 300 AU from the source

Strong-field tidal distortions of rotating black holes: Formalism and results for circular, equatorial orbits

Tidal coupling between members of a compact binary system can have an interesting and important influence on that binary's dynamical inspiral. Tidal coupling also distorts the binary's members, changing them (at lowest order) from spheres to ellipsoids. At least in the limit of fluid bodies and Newtonian gravity, there are simple connections between the geometry of the distorted ellipsoid and the impact of tides on the orbit's evolution. In this paper, we develop tools for investigating tidal distortions of rapidly rotating black holes using techniques that are good for strong-field, fast-motion binary orbits. We use black hole perturbation theory, so our results assume extreme mass ratios. We develop tools to compute the distortion to a black hole's curvature for any spin parameter, and for tidal fields arising from any bound orbit, in the frequency domain. We also develop tools to visualize the horizon's distortion for black hole spin $a/M \le \sqrt{3}/2$ (leaving the more complicated $a/M > \sqrt{3}/2$ case to a future analysis). We then study how a Kerr black hole's event horizon is distorted by a small body in a circular, equatorial orbit. We find that the connection between the geometry of tidal distortion and the orbit's evolution is not as simple as in the Newtonian limit.Comment: 37 pages, 8 figures. Accepted for publication to Physical Review D. This version corrects a number of typographical errors found when reviewing the page proof

Clues on black hole feedback from simulated and observed X-ray properties of elliptical galaxies

The centers of elliptical galaxies host supermassive black holes that significantly affect the surrounding interstellar medium through feedback resulting from the accretion process. The evolution of this gas and of the nuclear emission during the galaxies' lifetime has been studied recently with high-resolution hydrodynamical simulations. These included gas cooling and heating specific for an average AGN spectral energy distribution, a radiative efficiency declining at low mass accretion rates, and mechanical coupling between the hot gas and AGN winds. Here we present a short summary of the observational properties resulting from the simulations, focussing on 1) the nuclear luminosity; 2) the global luminosity and temperature of the hot gas; 3) its temperature profile and X-ray brightness profile. These properties are compared with those of galaxies of the local universe, pointing out the successes of the adopted feedback and the needs for new input in the simulations.Comment: 15 pages, 6 figures, accepted for publication in Advances in Space Researc

The Performance of US Bond Mutual Funds

We evaluate the performance of the US bond mutual fund industry using a comprehensive sample of bond funds over a long time period from January 1998 to February 2017. In this one study, we evaluate bond fund selectivity, market timing and performance persistence. We evaluate bond funds relative to their self-declared benchmarks and in terms of both gross-of-fee returns and net-of-fee returns. We document considerable abnormal performance among funds both to the fund (gross returns) and to the investor (net returns). Bond fund performance is found to be superior in the post financial crisis period. However, past strong performance cannot be relied upon to predict future performance. Finally, while some funds exhibit market timing ability; we find a predominance of negative market timing among US bond mutual funds

On the Influence of Magnetic Fields on the Structure of Protostellar Jets

We here present the first results of fully three-dimensional (3-D) MHD simulations of radiative cooling pulsed (time-variable) jets for a set of parameters which are suitable for protostellar outflows. Considering different initial magnetic field topologies in approximate $equipartition$ with the thermal gas, i.e., (i) a longitudinal, and (ii) a helical field, both of which permeating the jet and the ambient medium; and (iii) a purely toroidal field permeating only the jet, we find that the overall morphology of the pulsed jet is not very much affected by the presence of the different magnetic field geometries in comparison to a nonmagnetic calculation. Instead, the magnetic fields tend to affect essentially the detailed structure and emission properties behind the shocks at the head and at the pulse-induced internal knots, particularly for the helical and toroidal geometries. In these cases, we find, for example, that the $H_\alpha$ emissivity behind the internal knots can be about three to four times larger than that of the purely hydrodynamical jet. We also find that some features, like the nose cones that often develop at the jet head in 2-D calculations involving toroidal magnetic fields, are smoothed out or absent in the 3-D calculations.Comment: 13 pages, 3 figures, Accepted by ApJ Letters after minor corrections (for high resolution figures, see http://www.iagusp.usp.br/~adriano/h.tar

Fermi-LAT and Suzaku Observations of the Radio Galaxy Centaurus B

Centaurus B is a nearby radio galaxy positioned in the Southern hemisphere close to the Galactic plane. Here we present a detailed analysis of about 43 months of accumulated Fermi-LAT data of the gamma-ray counterpart of the source initially reported in the 2nd Fermi-LAT catalog, and of newly acquired Suzaku X-ray data. We confirm its detection at GeV photon energies, and analyze the extension and variability of the gamma-ray source in the LAT dataset, in which it appears as a steady gamma-ray emitter. The X-ray core of Centaurus B is detected as a bright source of a continuum radiation. We do not detect however any diffuse X-ray emission from the known radio lobes, with the provided upper limit only marginally consistent with the previously claimed ASCA flux. Two scenarios that connect the X-ray and gamma-ray properties are considered. In the first one, we assume that the diffuse non-thermal X-ray emission component is not significantly below the derived Suzaku upper limit. In this case, modeling the inverse-Compton emission shows that the observed gamma-ray flux of the source may in principle be produced within the lobes. This association would imply that efficient in-situ acceleration of the radiating electrons is occurring and that the lobes are dominated by the pressure from the relativistic particles. In the second scenario, with the diffuse X-ray emission well below the Suzaku upper limits, the lobes in the system are instead dominated by the magnetic pressure. In this case, the observed gamma-ray flux is not likely to be produced within the lobes, but instead within the nuclear parts of the jet. By means of synchrotron self-Compton modeling we show that this possibility could be consistent with the broad-band data collected for the unresolved core of Centaurus B, including the newly derived Suzaku spectrum.Comment: Accepted for publication in A&A. 11 page

Analysis of margin classification systems for assessing the risk of local recurrence after soft tissue sarcoma resection

Purpose: To compare the ability of margin classification systems to determine local recurrence (LR) risk after soft tissue sarcoma (STS) resection. Methods: Two thousand two hundred seventeen patients with nonmetastatic extremity and truncal STS treated with surgical resection and multidisciplinary consideration of perioperative radiotherapy were retrospectively reviewed. Margins were coded by residual tumor (R) classification (in which microscopic tumor at inked margin defines R1), the R+1mm classification (in which microscopic tumor within 1 mm of ink defines R1), and the Toronto Margin Context Classification (TMCC; in which positive margins are separated into planned close but positive at critical structures, positive after whoops re-excision, and inadvertent positive margins). Multivariate competing risk regression models were created. Results: By R classification, LR rates at 10-year follow-up were 8%, 21%, and 44% in R0, R1, and R2, respectively. R+1mm classification resulted in increased R1 margins (726 v 278, P < .001), but led to decreased LR for R1 margins without changing R0 LR; for R0, the 10-year LR rate was 8% (range, 7% to 10%); for R1, the 10-year LR rate was 12% (10% to 15%) . The TMCC also showed various LR rates among its tiers (P < .001). LR rates for positive margins on critical structures were not different from R0 at 10 years (11% v 8%, P = .18), whereas inadvertent positive margins had high LR (5-year, 28% [95% CI, 19% to 37%]; 10-year, 35% [95% CI, 25% to 46%]; P < .001). Conclusion: The R classification identified three distinct risk levels for LR in STS. An R+1mm classification reduced LR differences between R1 and R0, suggesting that a negative but < 1-mm margin may be adequate with multidisciplinary treatment. The TMCC provides additional stratification of positive margins that may aid in surgical planning and patient education

Crowding and Delivery of Healthcare in Emergency Departments: The European Perspective

Emergency department (ED) crowding is a multifactorial problem, resulting in increased ED waiting times, decreased patient satisfaction and deleterious domino effects on the entire hospital. Although difficult to define and once limited to anecdotal evidence, crowding is receiving more attention as attempts are made to quantify the problem objectively. It is a worldwide phenomenon with regional influences, as exemplified when analyzing the problem in Europe compared to that of the United States. In both regions, an aging population, limited hospital resources, staff shortages and delayed ancillary services are key contributors; however, because the structure of healthcare differs from country to country, varying influences affect the issue of crowding. The approach to healthcare delivery as a right of all people, as opposed to a free market commodity, depends on governmental organization and appropriation of funds. Thus, public funding directly influences potential crowding factors, such as number of hospital beds, community care facilities, and staffing. Ultimately ED crowding is a universal problem with distinctly regional root causes; thus, any approach to address the problem must be tailored to regional influences

‘The Remembering Group’; facilitating a cognitive stimulation group in an inpatient health and rehabilitation setting.

A trainee clinical psychologist and two occupational therapists reflect upon the experience of adapting a cognitive stimulation therapy group for an inpatient health and rehabilitation setting. The adaptations, benefits and challenges of implementing the group are discussed

Effect of Sodium-Glucose Cotransporter-2 Inhibitors on Endothelial Function: A Systematic Review of Preclinical Studies

IntroductionWhile the beneficial effects of sodium-glucose cotransporter-2 (SGLT-2) inhibitors on cardiovascular and renal outcomes are recognized, their direct effects on endothelial function remain unclear. We, therefore, undertook a systematic review to evaluate the current literature in this area.MethodsElectronic databases (PubMed, EMBASE, and Medline) were systematically searched using PRISMA guidelines for studies involving the in vitro, in vivo, or ex vivo administration of SGLT-2 inhibitors to animals, vascular tissue, or vascular endothelial cells.ResultsOf 144 retrieved publications, 24 experimental studies met the inclusion criteria. Reporting of possible sources of bias were poor, making the overall risk of bias difficult to assess. Within the 24 studies, the SGLT-2 inhibitors canagliflozin, ipragliflozin, empagliflozin, dapagliflozin, tofogliflozin, and luseogliflozin were assessed as interventions. Animal model studies (n = 17) demonstrated that all SGLT-2 inhibitors prevented endothelial dysfunction and enhanced endothelium-dependent vasorelaxation in diabetic and non-diabetic models. In vitro studies (n = 9) using human endothelial cells indicated a direct anti-inflammatory effect of dapagliflozin (1–100 nM) and canagliflozin, (10 µM), while empagliflozin (1 and 10 µM) improved viability of hyperglycemic cells. Potential mechanisms of action of the SGLT-2 inhibitors include a reduction in oxidative stress, modulation of adhesion molecules and reductions in pro-inflammatory cytokines.ConclusionsPreclinical studies indicate that SGLT-2 inhibitors attenuate vascular dysfunction in preclinical models via a combination of mechanisms that appear to act independently of glucose-lowering benefits